Skip to main content

Applications of pericyclic reactions||Biosynthesis of Vitamin D-D2-D3|ergocalciferol-cholecalciferol



Assalam o Alaikum in this lecture i am going to discuss Applications of pericyclic reactions OR Biosynthesis of Vitamin D-D2-D3. vitamin D2 is known as ergocalciferol and vitamin D3 is known as cholecalciferol. we synthesize cholecalciferol and ergocalciferol from their precurser. the precurser used are Ergosterol and 7-dehydrocholesterol.This lecture is delivered in Urdu ,Hindi and English. Vitamin D is the general name for two related compounds called cholecalciferol (vitamin D3) and ergocalciferol (vitamin D2). These two compounds differ in the identity of the side chain, R group.Vitamin D serves an important function in that it increases the body’s ability to metabolize the calcium present in the foods we eat. Calcium is essential because it is used in the formation of bones and teeth. A deficiency of vitamin D can cause the childhood disease called rickets, which is characterized by abnormal bone growth. Although most food does not contain substantial amounts of vitamin D, some food sources do contain the precursors that the body needs in order to synthesize vitamin D. Ergosterol is present in many vegetables, and 7-dehydrocholesterol is present in fish and dairy products.When the skin is exposed to sunlight, these precursors, located just beneath the skin, are converted into ergocalciferol and cholecalciferol respectively. For this reason, vitamin D is commonly called the “sunshine vitamin.” The precursors are converted into vitamin D via two successive pericyclic reactions.The first step is an electrocyclic ring-opening reaction, and the second step is a [1,7] sigmatropic rearrangement. This sequence of steps not only occurs in our bodies but is also utilized commercially to enrich milk with vitamin D3. All milk sold in the United States is irradiated with UV light, which converts the 7-dehydrocholesterol present in the milk into vitamin D3. Main contents that i have cover in this lecture are following:- 1) Applications of pericyclic reactions 2) Biosynthesis of Vitamin D &D2 &D3 by pericyclic reactions 3)Biosynthesis of ergocalciferol (vitamin D2) from Ergosterol . 4) Biosynthesis of cholecalciferol (vitamin D3) from 7-dehydrocholesterol 5)importance of pericyclic reactions 6) advantages of pericyclic reactions 7) pericyclic reactions importance in daily life. 8) structure of ergocalciferol (vitamin D2) 9) structure of cholecalciferol (vitamin D3 10)structure of Ergosterol 11)structure of 7-dehydrocholesterol Most useful videos for you:- 1-Chemical properties of Acid|Chemical reactions|10th class chemistry chapter 10|lecture in urdu,hindi https://youtu.be/cQkZE2IbQgo 2)Uses of pH, Chemistry Lecture | Authentic Education Channel|10th class chapter 10-Acid,Base & salts https://youtu.be/dM4UoP3Sw2Q 3)preservatives in food-How to preserve food at Home-A brief introduction|10th class chemistry lecture https://youtu.be/gKr1WWhK8PE 4)indicators/Methyl orange-litmus-Phenolphthalein/chemistry lecture in Urdu hindi and English|10TH https://youtu.be/s30Dqo1EnsY 5)uses of salts|10th class chemistry chapter 10|lecture in urdu hindi and english|Authentic education https://youtu.be/tXEUnvr7To0 6)Area of work for Analytical Chemists l10th class chemistry-chapter 10|lecture in Urdu,Hindi& English https://youtu.be/4N8hQhhX9ec 7) Uses of Bases-10th class chemistry|Lecture in Urdu,Hindi English|chapter 10|Authentic Education chan https://youtu.be/mt1wwsi5-j0 11)stomach acidity,hyperacidity,causes ,symptoms,prevention|10th class chemistry lecture in Urdu|online https://youtu.be/mYLL6PuUNQk 12)Removal of permanent hardness By using washing soda 10th class https://youtu.be/_6iukG1mZ1U 13)Removal of Temporary Water hardness by clarks method https://youtu.be/gO1fHgWhitY 14)Nucleophilic Aromatic substitution reactions https://www.youtube.com/playlist?list... 15)Electrophilic Aromatic substitution Reactions https://www.youtube.com/playlist?list... 16)10th class chemistry chapter 10 https://www.youtube.com/playlist?list... 17) 10th class chemistry chapter#15(water) https://www.youtube.com/playlist?list... 18)10th class chemistry chapter#9 chemical equilibrium https://www.youtube.com/playlist?list... Social Links :- Facebook:- https://web.facebook.com/Authentic-Ed... Twitter:- https://twitter.com/AuthenticEduca2 Blogger:- https://authenticchemist1.blogspot.com/ Whats App:- https://wa.me/923086683955 insta gram:- https://www.instagram.com/rashidshahz... #Applicationsofpericyclicreactions #BiosynthesisofVitaminDD2D3 #ergocalciferol #cholecalciferol #Ergosterol #7-dehydrocholesterol #AuthenticEducationChannel #organicchemistry

Comments

Popular posts from this blog

Chemical structure of endorphin

                   (Chemical structure of endorphin) It is the chemistry of 'carbon'-based compounds, but for some reason it does not cover elements such as carbon or' alloys' that contain carbon.  In addition, the importance of organometallic reagents such as Grubbs' catalyst  has increased in organic synthesis since the 20th century. But it can be regarded as an area of ​​inorganic chemistry. On the basis of the carbon-hydrogen bond, what is often regarded as an organic compound such as 'urea' becomes an inorganic compound. In fact, there is no fundamental difference between organic and inorganic compounds. Since the origin of the term 'organic chemistry' originated, it seems most comfortable to believe that the contents in the textbooks of university organic chemistry are organic chemistry. The word 'organic' is a sign of vitality that there is a fundamental difference between the substances that make up living things (most...

Jones Reagent, H2CrO4 Oxidation of Alcohols Reaction Mechanism Chromic Acid|breath analyzer applic

Assalam o Alaikum in this lecture i am going to discuss the reaction mechanism of the Jones Reagent which is used to oxidized primary alcohols into carboxylic acids and secondary alcohols into ketones. The jones reagent is composed of Chromium Trioxide CrO3, H2O, and H2SO4 (Sulfuric acid) which generates chromic acid H2CrO4. Oxidation of primary alcohols first generates an aldehyde which converts to the geminal / gem diol hydrate form which is then oxidized into a carboxylic acid. Tertiary alcohols are resistant to oxidation.This lecture is delivered in Urdu ,Hindi and English. 1° Alcohols are oxidized to carboxylic acids (RCOOH) under harsher reaction conditions: Na2Cr2O7, K2Cr2O7, or CrO3 in the presence of H2O and H2SO4. The mechanism for the oxidation of 1° alcohols to aldehydes parallels the oxidation of 2° alcohols to ketones detailed is discussed in this lecture. Oxidation of a 1o alcohol to a carboxylic acid requires three operations: oxidation first to the aldehyde, reac...

Benzyne Intermediate Reaction Mechanism - Nucleophilic Aromatic Substitution|NaNH2 and ammonia|chem

in this lecture i am going to discuss Prepration of benzyne or aryne by the reaction of chlorobenzene with NaNH2 and liquid ammonia.lecture in urdu ,hindi and english. This organic chemistry video tutorial discusses the reaction between chlorobenzene and with NaNH2 sodium amide And liquid ammonia to form aniline which proceeds via the aryne or benzyne intermediate. this reaction consists of two stages and each stage consists of two steps. stage 1 is the cis elimination of HX from vicinal position and formation of benzyne or aryne. stage 1 consists of step 1 and step 2. step 1 of stage 1 is extraction of proton by a base.step 2 of stage 1 is the elimination of halide ion (X) and formation of benzyne or aryne.stage 2 is the cis addition of base to benzyne or aryne. step 1 of stage 2 is the nucleiophilic attack on any triple bonded carbon of benzyne of aryne like -NH2 . step 2 of stage 2 is the the protonation of solvent from NH3 and formation of amino group -NH2 on benzene and ...